Treatment of Latent Tuberculosis Infection in a Kawasaki Disease Patient Receiving Anti-Tumor Necrosis Factor Alpha (TNFα) Therapy

Kawasaki disease (KD) is a common vasculitis syndrome that mainly affects children. Latent tuberculosis infection (LTBI) is a tuberculosis (TB) infection without signs or symptoms. Here, we report the case of a boy who traveled from abroad, was diagnosed with KD at our hospital, and underwent multidisciplinary treatment, including anti-TNFα therapy. Subsequently, the patient was found to have LTBI and was administered anti-TB treatment. To the best of our knowledge, this is the first reported case of LTBI in a KD patient receiving immunosuppressive therapy containing anti-TNFα.

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Publication Details

Journal
Cureus
Published
2024-09-28
DOI
https://doi.org/10.7759/cureus.70407
Citations
2
Primary Topic
Kawasaki Disease and Coronary Complications
Type
article
Field-Weighted Citation Impact
1.15

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article

Treatment of Latent Tuberculosis Infection in a Kawasaki Disease Patient Receiving Anti-Tumor Necrosis Factor Alpha (TNFα) Therapy

Mitsukazu Mamada, Toshinari Yakuo, Koji Yokoyama
2 citations
Cureus
Kawasaki Disease and Coronary Complications
1.15
article

Treatment of Latent Tuberculosis Infection in a Kawasaki Disease Patient Receiving Anti-Tumor Necrosis Factor Alpha (TNFα) Therapy

Mitsukazu Mamada, Toshinari Yakuo, Koji Yokoyama
article en
2 citations

Abstract

Kawasaki disease (KD) is a common vasculitis syndrome that mainly affects children. Latent tuberculosis infection (LTBI) is a tuberculosis (TB) infection without signs or symptoms. Here, we report the case of a boy who traveled from abroad, was diagnosed with KD at our hospital, and underwent multidisciplinary treatment, including anti-TNFα therapy. Subsequently, the patient was found to have LTBI and was administered anti-TB treatment. To the best of our knowledge, this is the first reported case of LTBI in a KD patient receiving immunosuppressive therapy containing anti-TNFα.

CureusVol. 16(9)
Japanese Red Cross Society Wakayama Medical Center (JP)
Tokyo Medical and Dental University
Good health and well-being
Openalex Percentile: Top 20%
Kawasaki Disease and Coronary Complications
1.15
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