Two-photon optogenetics-based assessment of neuronal connectivity in healthy and chronic hypoperfusion mice
We successfully developed a direct method to evaluate neuronal connectivity in the living brain using two-photon optogenetics. The technique was successful in detecting connectivity impairment in hypoperfusion model mice.
Authors
- Manami Takahashi (ORCID: https://orcid.org/0000-0003-0829-8780)
- Masaki Yoshioka (ORCID: https://orcid.org/0009-0009-9672-1374)
- Hiroyuki Takuwa (ORCID: https://orcid.org/0000-0003-1166-9845)
- Mariko Handa
- Jeff Kershaw
- Ayaka Takada
Institutions
- National Institutes for Quantum Science and Technology (JP)
Publication Details
- Journal
- Neurophotonics
- Published
- 2024-09-28
- DOI
- https://doi.org/10.1117/1.nph.11.3.035009
- Primary Topic
- Neurological Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of Education, Culture, Sports, Science and Technology
- Chiba University