Fecal microbiota transplantation from patients with polycystic ovary syndrome induces metabolic disorders and ovarian dysfunction in germ-free mice
Our findings suggest that the microbiome may govern the set point of PCOS-bearing individuals and that gut ecosystem manipulation may be a useful marker and target for the management of PCOS.
Authors
- Feiling Huang (ORCID: https://orcid.org/0000-0002-4464-3599)
- Ruiyi Tang (ORCID: https://orcid.org/0000-0001-7091-7832)
- Yuzhoujia Deng
- Rong Chen (ORCID: https://orcid.org/0000-0001-8751-9590)
- Miao Zhou
- Peng Zhang (ORCID: https://orcid.org/0000-0001-7002-7442)
Institutions
- Beijing Tongren Hospital (CN)
- Capital Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- Beijing Children’s Hospital (CN)
- Cloud Computing Center (CN)
Publication Details
- Journal
- BMC Microbiology
- Published
- 2024-09-28
- DOI
- https://doi.org/10.1186/s12866-024-03513-z
- Citations
- 20
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 4.68
Funders
- National Natural Science Foundation of China
- Chinese Academy of Medical Sciences
- Peking Union Medical College Hospital
- Peking Union Medical College
- National Key Research and Development Program of China
- SLAC National Accelerator Laboratory