Long-Term Vonoprazan and Acotiamide-Refractory Patients With Functional Dyspepsia Partly Exhibit Pancreatic Enzyme Abnormalities

Long-term vonoprazan alone or vonoprazan and acotiamide combination therapy significantly improved each FD symptom. The OTE in patients treated with vonoprazan alone or vonoprazan and acotiamide combination therapy was only 50%. Long-term vonoprazan and acotiamide combination therapy may differentiate patients with pancreatic enzyme abnormalities from those with FD.

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Publication Details

Journal
Cureus
Published
2024-09-28
DOI
https://doi.org/10.7759/cureus.70371
Citations
2
Primary Topic
Gastrointestinal motility and disorders
Type
article
Field-Weighted Citation Impact
0.93
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article

Long-Term Vonoprazan and Acotiamide-Refractory Patients With Functional Dyspepsia Partly Exhibit Pancreatic Enzyme Abnormalities

Takeshi Onda, Shuhei Agawa, Rie Kawawa, Seiji Futagami et al.
2 citations
Cureus
Gastrointestinal motility and disorders
0.93
article

Long-Term Vonoprazan and Acotiamide-Refractory Patients With Functional Dyspepsia Partly Exhibit Pancreatic Enzyme Abnormalities

Takeshi Onda, Shuhei Agawa, Rie Kawawa, Seiji Futagami, Katsuhiko Iwakiri, Mayu Habiro, Ken Nakamura, Nobue Ueki, S. Higashida
article en
2 citations

Abstract

Long-term vonoprazan alone or vonoprazan and acotiamide combination therapy significantly improved each FD symptom. The OTE in patients treated with vonoprazan alone or vonoprazan and acotiamide combination therapy was only 50%. Long-term vonoprazan and acotiamide combination therapy may differentiate patients with pancreatic enzyme abnormalities from those with FD.

CureusVol. 16(9)
Nippon Medical School Hospital (JP), Nippon Medical School (JP)
Zero hunger
Openalex Percentile: Top 24%
Gastrointestinal motility and disorders
0.93
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