Prognostic role of pre-diagnostic circulating inflammatory biomarkers in breast cancer survival: evidence from the EPIC cohort study
Higher pre-diagnosis IL-6 levels suggest poorer long-term survival among BC survivors. In postmenopausal survivors, elevated IL-6, IL-10, and TNFα and inflammatory scores seem to predict all-cause mortality.
Authors
- Manon Cairat (ORCID: https://orcid.org/0000-0002-0964-3120)
- Alicia K. Heath (ORCID: https://orcid.org/0000-0001-6517-1300)
- Sofia Christakoudi (ORCID: https://orcid.org/0000-0001-9219-4436)
- Sabina Rinaldi (ORCID: https://orcid.org/0000-0002-6846-1204)
- Claudia Agnoli (ORCID: https://orcid.org/0000-0003-4472-1179)
- Antonio Agudo (ORCID: https://orcid.org/0000-0001-9900-5677)
- Lene Mellemkjær (ORCID: https://orcid.org/0000-0001-9222-6215)
- Rudolf Kaaks (ORCID: https://orcid.org/0000-0003-3751-3929)
- Mariem Hajji-Louati
- Carlotta Sacerdote (ORCID: https://orcid.org/0000-0002-8008-5096)
- Matthias Bernd Schulze (ORCID: https://orcid.org/0000-0002-0830-5277)
- Karl Smith-Byrne (ORCID: https://orcid.org/0000-0002-1932-7463)
- Charlotte Le Cornet (ORCID: https://orcid.org/0000-0002-5291-7545)
- Giovanna Masala (ORCID: https://orcid.org/0000-0002-5758-9069)
- Marcela Guevara (ORCID: https://orcid.org/0000-0001-9242-6364)
- Francesca Romana Mancini (ORCID: https://orcid.org/0000-0003-2297-3869)
- Laure Dossus (ORCID: https://orcid.org/0000-0003-2716-5748)
- Marc J. Gunter (ORCID: https://orcid.org/0000-0001-5472-6761)
- Carlota Castro‐Espín (ORCID: https://orcid.org/0000-0001-9050-7590)
- Anne‐Sophie Navionis (ORCID: https://orcid.org/0009-0002-9854-1114)
- Christian S. Antoniussen
- Christina C. Dahm (ORCID: https://orcid.org/0000-0003-0481-2893)
- Marta Crous‐Bou (ORCID: https://orcid.org/0000-0003-1493-4288)
- Pilar Amiano (ORCID: https://orcid.org/0000-0003-3986-7026)
- Anne Marie Tjønneland (ORCID: https://orcid.org/0000-0003-4385-2097)
- Maria-Jose Sánchez
- María‐Dolores Chirlaque
- Gianluca Severi
Institutions
- Università degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT)
- University of Copenhagen (DK)
- Harvard University (US)
- Inserm (FR)
- University of Potsdam (DE)
- German Cancer Research Center (DE)
- Université de Versailles Saint-Quentin-en-Yvelines (FR)
- Aarhus University (DK)
- Heidelberg University (DE)
- Université Paris-Saclay (FR)
- Basque Government (ES)
- Prevention Institute (US)
- Bellvitge University Hospital (ES)
- University of Oxford (GB)
- Instituto de Salud Pública de Navarra (ES)
- Institut d'Investigació Biomédica de Bellvitge (ES)
- Ministry of Health (ES)
- Biogipuzkoa Health Research Institute (ES)
- Centre de recherche en Epidémiologie et Santé des Populations (FR)
- Institut Català d'Oncologia (ES)
- Navarre Institute of Health Research (ES)
- Instituto de Investigación Biosanitaria de Granada (ES)
- Instituto Murciano de Investigación Biosanitaria (ES)
- Danish Cancer Society (DK)
- Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (ES)
- Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
- Novamont (Italy) (IT)
- German Institute of Human Nutrition (DE)
- Centre international de recherche sur le cancer (FR)
- Imperial College London (GB)
- Andalusian School of Public Health (ES)
Publication Details
- Journal
- British Journal of Cancer
- Published
- 2024-09-28
- DOI
- https://doi.org/10.1038/s41416-024-02858-6
- Citations
- 5
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.41
Funders
- World Health Organization
- Centres de Recerca de Catalunya
- Fundación Científica Asociación Española Contra el Cáncer
- Generalitat de Catalunya
- Instituto de Salud Carlos III
- Rijksinstituut voor Volksgezondheid en Milieu