Assessing disease progression in ALS: prognostic subgroups and outliers
Our study reaffirms ΔFS as a prognostic biomarker for ALS. We disclosed outliers defying anticipated patterns. The observed shift in progression categories underscores the non-linear nature of disease progression. Genetic and unknown biological reasons may explain these deviations. Further research is needed to fully understand modulation of ALS survival.
Authors
- Mamede de Carvalho (ORCID: https://orcid.org/0000-0001-7556-0158)
- Marta Gromicho (ORCID: https://orcid.org/0000-0003-2111-4579)
- Miguel Oliveira Santos (ORCID: https://orcid.org/0000-0002-8290-0410)
- Susana Pinto (ORCID: https://orcid.org/0000-0002-0727-5897)
- Inês Alves (ORCID: https://orcid.org/0000-0002-7146-414X)
Institutions
- University of Lisbon (PT)
- Hospital de Santa Maria (PT)
Publication Details
- Journal
- Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- Published
- 2024-09-28
- DOI
- https://doi.org/10.1080/21678421.2024.2407412
- Citations
- 7
- Primary Topic
- Amyotrophic Lateral Sclerosis Research
- Type
- article
- Field-Weighted Citation Impact
- 2.58