Metabolomics of basal tears in amyotrophic lateral sclerosis: A cross-sectional study
This study represents the first prospective analysis of basal tear metabolomics in individuals with ALS. Despite the inability to distinguish between ALS patients and controls based on metabolic signatures, these findings could contribute to understanding the phenotypic diversity of ALS. Notably, distinct metabolic profiles were identified that differentiate between the bulbar and spinal forms of the disease.
Authors
- S. Beltran (ORCID: https://orcid.org/0000-0003-4718-0902)
- Camille Dupuy (ORCID: https://orcid.org/0000-0003-0063-4380)
- Antoine Lefèvre (ORCID: https://orcid.org/0009-0003-9032-1085)
- Hélène Blasco (ORCID: https://orcid.org/0000-0001-6107-0035)
- Sophie Catanese (ORCID: https://orcid.org/0000-0001-6741-9402)
- Patrick Emond (ORCID: https://orcid.org/0000-0002-5324-2164)
- Raoul Kanav Khanna (ORCID: https://orcid.org/0000-0001-6032-1488)
- Pierre‐Jean Pisella (ORCID: https://orcid.org/0000-0002-9729-5444)
- Valérie Gissot (ORCID: https://orcid.org/0000-0002-0091-8159)
- Geoffroy Mortemousque (ORCID: https://orcid.org/0009-0004-1151-3175)
- Philippe Corcia
Institutions
- Université de Tours (FR)
- Inserm (FR)
- Centre Hospitalier Universitaire de Tours (FR)
- Hôpital Bretonneau (FR)
- Clinical Investigation Center Plurithematic Tours (FR)
Publication Details
- Journal
- The Ocular Surface
- Published
- 2024-09-28
- DOI
- https://doi.org/10.1016/j.jtos.2024.09.005
- Citations
- 2
- Primary Topic
- Amyotrophic Lateral Sclerosis Research
- Type
- article
- Field-Weighted Citation Impact
- 0.74