Androgen Effects on Alcohol-induced Liver Fibrosis Are Controlled by a Notch-dependent Epigenetic Switch
Male sex hormone signaling can promote or prevent alcohol-associated liver fibrosis depending on the KDM5-dependent epigenetic state.
Authors
- Adriana Rodriguez (ORCID: https://orcid.org/0009-0002-7315-6594)
- Steven A. Weinman (ORCID: https://orcid.org/0000-0002-8744-8873)
- Irina Tikhanovich (ORCID: https://orcid.org/0000-0003-1041-8032)
- Michael Schonfeld (ORCID: https://orcid.org/0009-0001-7393-6876)
- Madhulika Sharma (ORCID: https://orcid.org/0000-0001-7488-5444)
- K.S. Nataraj
Institutions
- Estonian Information Technology College (EE)
- Kansas City VA Medical Center (US)
Publication Details
- Journal
- Cellular and Molecular Gastroenterology and Hepatology
- Published
- 2024-09-28
- DOI
- https://doi.org/10.1016/j.jcmgh.2024.101414
- Citations
- 9
- Primary Topic
- Liver physiology and pathology
- Type
- article
- Field-Weighted Citation Impact
- 3.33
Funders
- U.S. Department of Veterans Affairs
- National Institute on Alcohol Abuse and Alcoholism