Deciphering the possible role of MmpL7 efflux pump in SQ109 resistance in Mycobacterium tuberculosis
Our data demonstrated that SQ109 exhibited excellent levels of in vitro activity against MTB. MmpL7 may be a potential gene for MTB resistance to SQ109, providing a useful target for detecting SQ109 resistance in MTB.
Authors
- Jinfeng Yuan
- Wenhui Shi (ORCID: https://orcid.org/0000-0002-9903-2138)
- Xuxia Zhang (ORCID: https://orcid.org/0000-0002-5888-4019)
- Naihui Chu (ORCID: https://orcid.org/0000-0002-7468-1705)
- Yuanyuan Shang (ORCID: https://orcid.org/0000-0002-3538-7730)
- Cong Yao
- Jing Wei (ORCID: https://orcid.org/0000-0002-7399-4136)
- Jie Lu (ORCID: https://orcid.org/0000-0001-5274-8035)
- Fuzhen Zhang (ORCID: https://orcid.org/0000-0002-5056-3886)
Institutions
- Shandong University (CN)
- Beijing Chest Hospital (CN)
- Beijing Children’s Hospital (CN)
Publication Details
- Journal
- Annals of Clinical Microbiology and Antimicrobials
- Published
- 2024-09-28
- DOI
- https://doi.org/10.1186/s12941-024-00746-8
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00