Novel functionalized acylation reagents for Glyand Lys-His tag acylation on proteins
Increasing the sum of Hammett parameters of the phenol substituents in the esters give a linear decrease in hydrolysis half-life of esters This also gave more non-specific acylation of model peptides RESULTS AND DISCUSSION
Authors
- Tuule Treiberg (ORCID: https://orcid.org/0000-0003-3070-9144)
- Christian Kofoed (ORCID: https://orcid.org/0000-0002-8258-5887)
- Mikkel B. Thygesen (ORCID: https://orcid.org/0000-0002-0158-2802)
- Knud J. Jensen (ORCID: https://orcid.org/0000-0003-3525-5452)
- Delphine Nørgaard Møller (ORCID: https://orcid.org/0000-0001-6764-1193)
- Kasper K. Sørensen
Institutions
- Usak University (TR)
Publication Details
- Published
- 2024-09-20
- DOI
- https://doi.org/10.17952/37eps.2024.p2172
- Primary Topic
- Chemical Synthesis and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00