Effects of adipose tissues on the relationship between type 2 diabetes mellitus and reduced heart rate variability: mediation analysis
Epicardial adipose tissue partially mediated the relationship between T2DM and reduced HRV, which reinforces the value of targeting heart-specific visceral fat to prevent cardiac autonomic neuropathy in diabetes.
Authors
- Xiaolan Ouyang
- Zhuoshan Huang (ORCID: https://orcid.org/0000-0002-1128-3224)
- Bingyuan Wu (ORCID: https://orcid.org/0000-0002-3440-7277)
- Jiafu Wang (ORCID: https://orcid.org/0000-0002-3654-4400)
- Hongxing Wu (ORCID: https://orcid.org/0000-0002-0304-0740)
- Yan Lü (ORCID: https://orcid.org/0000-0002-5893-6114)
- Yue Li (ORCID: https://orcid.org/0000-0001-8198-9911)
- Tongtong Wang (ORCID: https://orcid.org/0000-0002-8807-2441)
- Junlin Zhong
- Suhua Li (ORCID: https://orcid.org/0000-0003-4611-6829)
- Long Peng (ORCID: https://orcid.org/0000-0002-2716-4537)
- Lin Wu (ORCID: https://orcid.org/0000-0002-2630-6521)
- Xixiang Tang
Institutions
- Sun Yat-sen University (CN)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- Third Affiliated Hospital of Sun Yat-sen University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2024-09-28
- DOI
- https://doi.org/10.1186/s12933-024-02438-1
- Citations
- 9
- Primary Topic
- Heart Rate Variability and Autonomic Control
- Type
- article
- Field-Weighted Citation Impact
- 3.62
Funders
- National Natural Science Foundation of China
- Basic and Applied Basic Research Foundation of Guangdong Province