The factors associated with mortality in sepsis adult patients at Hue Central Hospital 2021 - 2022

Background: Sepsis has a high risk of mortality. Diagnosing and prognosing sepsis in the early stage play an important role, helping to reduce mortality and shorten the time of hospital stay of patients. Aims: Study the factors associated with mortality in sepsis adult patients.Methods: 110 patients over 15 years old were diagnosed with sepsis, at the Department of Tropical Diseases and Intensive Care Unit, Hue Central Hospital from 1/2021 to 12/2022. Tracked cross-sectional descriptive study.Results: The median age of sepsis patients was 66.4 ± 17.5. Male/female: 62/48. The duration of onset of the disease was about 3 days. The average length of hospital stay was 2 weeks. The rates of septic shock and multi-organ failure were 32.0% and 35.5%, respectively. The mortality rate was 20.0%. The heart, liver, respiratory, and kidney are the organs with the highest rates of dysfunction. There was a statistically significant difference in the time of hospital stay, the number of dysfunction organ, serum urea and creatinine between the two groups of death and survivors (p < 0.01). The SOFA score of patients who died gradually increased compared to the SOFA score at the admission, the survivors had a decrease in SOFA scores over time.Conclusions: The majority of sepsis patients > 60 years old (66.4%), the proportion of males was higher than females. The rates of septic shock and multiple organ failure were 31.8% and 35.5%, respectively. The mortality rate was 20.0%. The heart, liver, respiratory, and kidney are the organs with the highest rates of organ failure. Factors that were independently associated with mortality in sepsis patients were SOFA_T24, serum creatinine and number of dysfunctional organs.