Determining the rate and overlap of the criteria of fasting blood glucose, 2-hour blood glucose after oral glucose tolerance test and HbA1c in the diagnostic of prediabetes in people at risk in Vietnam

Objectives: Determine the rate of prediabetes based on fasting blood glucose concentration (G0), blood glucose concentration 2 hours after oral glucose tolerance test (G2) and HbA1c value and evaluate the overlap when using criteria in diagnosing prediabetes in the study group.Methods: A cross-sectional descriptive study on 1899 patients ≥ 18 years old with risk factors of prediabetes or diabetes according to criteria of Vietnam Ministry of Health at 05 hospitals in Vietnam: Hanoi Heart Hospital, National Hospital of Endocrinology, Nghe An Endocrinology Hospital, Ho Chi Minh City Heart Institute and Hue Central Hospital from April 2020 to August 2023. Include in the study the cases satisfying the selection criteria. Perform an oral glucose tolerance test: determine blood glucose at two times G0, G2 and test HbA1c. Data processing using SPSS 26.0 software.Results: The rate of prediabetes in the study group was 83.92%. Of which, the diagnosis of prediabetes based on HbA1C criteria had the highest rate (48.64%), followed by meeting G2 criteria (48.07%) and the lowest was meeting G0 criteria (47.59%). When using additional G2 or HbA1C criteria to determine prediabetes compared to the group using only 1 G0 criterion, the rate increased by 0.48% or 1.05%, respectively. When using the combined criteria of G0 or G2 and G2 or HbA1C to determine prediabetes compared to the group using the combined criteria of G0 or HbA1C, the rate decreased by 1.53% and 0.8%, respectively.Conclusion: People at risk are at high risk of developing prediabetes. It should be paid attention to the managing and treating people at risk.