Cervical Papillary Adenofibroma: A Rare Case Report

This study presents a rare instance of cervical papillary adenofibroma, a benign biphasic neoplasm originating from glandular and fibrous tissue, occurring in a 43-year-old female patient. Most common site is the endometrium. Papillary adenofibroma arising from the cervix is an infrequent entity. Uterine adenofibromas were first described by Ober in 1959 as a form of mixed mesodermal tumor. Cervical adenofibromas was first described by Abell in 1971. Both the stromal and epithelial components are benign. Grossly, adenofibroma present as a papillary, polypoidal or sessile lesion that may protrude into the endocervical canal with cut surface showing multiple cysts imparting it a spongy appearance. Microscopically, they have a nodular surface with a lobulated papillary configuration. The tumor may recur if incompletely excised. Adenosarcoma and adenomyoma are important differential diagnosis. The clinical presentation, diagnostic procedures, gross appearance, microscopic architecture, and management strategies are elucidated in this case report. Emphasizing the significance of accurate diagnosis and tailored treatment, this case report underscores the importance of recognizing and managing such infrequent cervical tumors. Through this case report, our aim is to contribute to the existing medical literature on cervical papillary adenofibromas, shedding light on its clinical characteristics, diagnostic nuances, and management modalities for the benefit of clinicians and researchers encountering similar cases. Keywords: Adenofibroma, Adenosarcoma, Benign, Cervix, Papillary, Rare