Hemodynamics study of anterior cerebral artery with different sac centerline lengths for rupture risk assessment

The present research extensively investigates the significance of the sac centerline length of the anterior cerebral artery (ACA) on aneurysm rupture risk. Hemodynamic factors influencing aneurysm rupture are assessed to identify critical regions prone to rupture. Wall shear stress is analyzed by modeling blood flow in three real saccular ACA cases with varying sac centerline lengths. A one-way fluid-solid interaction (FSI) model is employed to examine the interaction between blood flow and vessel deformation. The computational study reveals that wall shear stress on the ACA saccular aneurysm wall is significantly higher when the sac centerline length is shorter. Conversely, the mean oscillatory index changes with different sac centerline lengths, showing that an increase in sac centerline length leads to higher blood oscillation within the sac area in ACA cases.

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Publication Details

Journal
Scientific Reports
Published
2024-09-28
DOI
https://doi.org/10.1038/s41598-024-73231-z
Citations
1
Primary Topic
Traumatic Brain Injury and Neurovascular Disturbances
Type
article
Field-Weighted Citation Impact
0.37
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Hemodynamics study of anterior cerebral artery with different sac centerline lengths for rupture risk assessment

Zeshang Guo, Hengtong Wan, Zhenjin Su, Yanhua Liu et al.
1 citations
Scientific Reports
Traumatic Brain Injury and Neurovascular Disturbances
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article

Hemodynamics study of anterior cerebral artery with different sac centerline lengths for rupture risk assessment

Zeshang Guo, Hengtong Wan, Zhenjin Su, Yanhua Liu, Weiyan Teng
article en
1 citations

Abstract

The present research extensively investigates the significance of the sac centerline length of the anterior cerebral artery (ACA) on aneurysm rupture risk. Hemodynamic factors influencing aneurysm rupture are assessed to identify critical regions prone to rupture. Wall shear stress is analyzed by modeling blood flow in three real saccular ACA cases with varying sac centerline lengths. A one-way fluid-solid interaction (FSI) model is employed to examine the interaction between blood flow and vessel deformation. The computational study reveals that wall shear stress on the ACA saccular aneurysm wall is significantly higher when the sac centerline length is shorter. Conversely, the mean oscillatory index changes with different sac centerline lengths, showing that an increase in sac centerline length leads to higher blood oscillation within the sac area in ACA cases.

Scientific ReportsVol. 14(1)
First Bethune Hospital of Jilin University (CN)
Good health and well-being
Openalex Percentile: Top 35%
Traumatic Brain Injury and Neurovascular Disturbances
0.37
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