Functional gene signature offers a powerful tool for characterizing clinicopathological features and depicting tumor immune microenvironment of colorectal cancer
This study introduces a functional gene signature that effectively and reliably predicts clinicopathological features and the tumor immune microenvironment in colorectal cancer. Moreover, the identification of TPM2 as a potential biomarker for CAFs holds promising implications for future research and clinical applications in the field of colorectal cancer.
Authors
- Zhenzhong Fa (ORCID: https://orcid.org/0000-0003-0646-5637)
- Jie Zhou (ORCID: https://orcid.org/0000-0001-5964-1599)
- Yue Wang (ORCID: https://orcid.org/0000-0002-1800-4814)
- Yixin Xu (ORCID: https://orcid.org/0000-0003-2164-1483)
- Ziyan Zhu (ORCID: https://orcid.org/0000-0002-2069-5001)
- Jikun Li (ORCID: https://orcid.org/0000-0001-5613-3222)
- Xuezhong Xu
Institutions
- Jiangsu University (CN)
- Xuzhou Medical College (CN)
- Shanghai Jiao Tong University (CN)
- Shanghai First People's Hospital (CN)
- Changzhou University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2024-09-28
- DOI
- https://doi.org/10.1186/s12885-024-12996-y
- Citations
- 5
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 1.41
Funders
- Jiangsu University