Assessment and Evaluation of Contemporary Approaches for Astrocyte Differentiation from hiPSCs: A Modeling Paradigm for Alzheimer's Disease
Overall, our analyses highlight the need to consider the advantages and disadvantages of a given differentiation protocol for solving specific research tasks or drug discovery studies with iPSC-derived astrocytes.
Authors
- Martina Zapletalová (ORCID: https://orcid.org/0000-0003-3118-2647)
- Radek Kučera (ORCID: https://orcid.org/0000-0002-2739-2302)
- Melinda Zana (ORCID: https://orcid.org/0000-0001-5725-1300)
- Balázs Széky (ORCID: https://orcid.org/0009-0002-9561-1957)
- Shashank Pandey (ORCID: https://orcid.org/0000-0001-8043-130X)
- Jiřı́ Hudeček (ORCID: https://orcid.org/0000-0003-0082-482X)
- Jan Lochman (ORCID: https://orcid.org/0000-0003-4420-8842)
- Omar Šerý (ORCID: https://orcid.org/0000-0002-6062-8997)
- András Dinnyés (ORCID: https://orcid.org/0000-0003-3791-2583)
- Veronika Juráková (ORCID: https://orcid.org/0000-0002-5921-7015)
- Anita Fehér (ORCID: https://orcid.org/0000-0002-7832-0886)
Institutions
- Magyar Agrár- és Élettudományi Egyetem (HU)
- Charles University (CZ)
- Masaryk University (CZ)
- Czech Academy of Sciences, Institute of Animal Physiology and Genetics (CZ)
- BioTalentum (Hungary) (HU)
Publication Details
- Journal
- Biological Procedures Online
- Published
- 2024-09-28
- DOI
- https://doi.org/10.1186/s12575-024-00257-y
- Citations
- 2
- Primary Topic
- Neurogenesis and neuroplasticity mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.82
Funders
- Ministerstvo Zdravotnictví Ceské Republiky