Biphasic effects of single-dose intravenous injection of uridine adenosine tetraphosphate on blood pressure in mice
Compared to NA and α, β-meATP, Up<sub>4</sub>A, which contains purine and pyrimidine components, displayed a weaker blood pressure-elevating potency. Through its corresponding structure, Up<sub>4</sub>A exerted vasodilatory and vasoconstrictive effects throughout the entire experiment resulting in biphasic changes in blood pressure.
Authors
- Kailin Li
- Li Lu (ORCID: https://orcid.org/0000-0003-2523-3372)
- Lu Gan (ORCID: https://orcid.org/0000-0001-8665-2760)
- Yue Ma (ORCID: https://orcid.org/0000-0003-1639-465X)
- Chen-Yang An
- Xinxin Wang (ORCID: https://orcid.org/0009-0000-8884-9639)
Institutions
- Chengde Medical University (CN)
- Affiliated Hospital of Hebei University (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2024-09-28
- DOI
- https://doi.org/10.1186/s40001-024-02038-5
- Citations
- 1
- Primary Topic
- Adenosine and Purinergic Signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.40
Funders
- Hebei University