Successful fat transplant in a rare acquired lipodystrophy Barraquer–Simons syndrome

Lipodystrophies can be generalized and partial/localized lack of subcutaneous tissue, which are uncommon heterogeneous illnesses that can be hereditary or acquired. Acquired partial lipodystrophy’ (APL) is the new name for lipodystrophia progressiva, also known as Barraquer–Simons syndrome (BSS). It could come after a severe viral infection like the measles. Young people and children both experience it. Typically, BSS or APL starts between the ages of 5 and 15. The principal feature of BSS is cephalothoracic lipodystrophy, which affects the face, neck, arms, thorax, and upper abdomen in a cephalocaudal pattern. Alternate complement pathway activation and C3 hypocomplementemia with adipocyte lysis brought on by complement 3 nephritic factor (C3NeF) have been suggested as potential causes of fat loss in individuals with APL, even though the precise process is still mostly understood. Therapeutic options for lipodystrophy include fat fillers. Different types of autologous fat transplants are possible. Autologous free fat graft where a mass of tissue harvested from any discrete subcutaneous location and implanted at a recipient site. Dermofat grafts are made from tissue that has been removed from a region, allowing for the removal of full-thickness skin grafts and the primary closure of defects. The dermofat graft can be employed as a spacer between gliding tissues or as a filler. Omental flaps, which are revascularized fat flaps, can be utilized for microvascular transfer, soft-tissue filler for hemifacial atrophy, or to cover any significant skin defects. When fat is extracted, processed, and transplanted in liquid injectable form for a variety of purposes, it is known as free fat injection.