PRKACB is a novel imprinted gene in marsupials
We conclude that PRKACB is a novel, DMR-associated marsupial imprinted gene. Imprinting of PRKACB in marsupials and GNAS in eutherians may indicate a conserved selection pressure for imprinting of the protein kinase A signalling pathway in therians with the two lineages adapting by imprinting different genes.
Authors
- Trent Newman (ORCID: https://orcid.org/0000-0002-6767-1429)
- Timothy A. Hore (ORCID: https://orcid.org/0000-0002-6735-225X)
- Geoff Shaw (ORCID: https://orcid.org/0000-0002-7421-7136)
- Donna M. Bond (ORCID: https://orcid.org/0000-0001-7704-1263)
- Marilyn B. Renfree (ORCID: https://orcid.org/0000-0002-4589-0436)
- Quentin A. Gouil (ORCID: https://orcid.org/0000-0002-5142-7886)
- Teruhito Ishihara (ORCID: https://orcid.org/0000-0002-2207-2473)
- Phoebe Rizzoli
Institutions
- Babraham Institute (GB)
- The University of Melbourne (AU)
- Walter and Eliza Hall Institute of Medical Research (AU)
- University of Otago (NZ)
Publication Details
- Journal
- Epigenetics & Chromatin
- Published
- 2024-09-28
- DOI
- https://doi.org/10.1186/s13072-024-00552-8
- Citations
- 5
- Primary Topic
- Genetic Syndromes and Imprinting
- Type
- article
- Field-Weighted Citation Impact
- 2.75
Funders
- Australian Research Council