Chronic lymphoproliferative disorder of natural killer cells-related neurolymphomatosis with severe autonomic dysfunction: a case report

We experienced a case of pathologically diagnosed neurolymphomatosis with autonomic dysfunction associated with CLPD-NK. In cases of subacute to chronic autonomic dysfunction, paraneoplastic neuropathy, amyloidosis, and autoimmune autonomic ganglionopathy are considered; however neurolymphomatosis caused by CLPD-NK, an important cause of autonomic dysfunction, is not. In difficult to make diagnosis, aggressive nerve biopsy is required.

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Publication Details

Journal
BMC Neurology
Published
2024-09-28
DOI
https://doi.org/10.1186/s12883-024-03879-7
Primary Topic
CNS Lymphoma Diagnosis and Treatment
Type
article
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article

Chronic lymphoproliferative disorder of natural killer cells-related neurolymphomatosis with severe autonomic dysfunction: a case report

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Chronic lymphoproliferative disorder of natural killer cells-related neurolymphomatosis with severe autonomic dysfunction: a case report

S. N. Nakamura, Masahisa Katsuno, Takashi Inoue, Yutaka Tsutsumi, Ichiro Yabe, Kazuhiro Horiuchi, Satoru Munakata, Yuki Fukami, Kazuki Yamada, Satoru Yagi
article en

Abstract

We experienced a case of pathologically diagnosed neurolymphomatosis with autonomic dysfunction associated with CLPD-NK. In cases of subacute to chronic autonomic dysfunction, paraneoplastic neuropathy, amyloidosis, and autoimmune autonomic ganglionopathy are considered; however neurolymphomatosis caused by CLPD-NK, an important cause of autonomic dysfunction, is not. In difficult to make diagnosis, aggressive nerve biopsy is required.

BMC NeurologyVol. 24(1)
Hokkaido University (JP), Hakodate National Hospital (JP), Nagoya University (JP)
Zero hunger
Openalex Percentile: Top 74%
CNS Lymphoma Diagnosis and Treatment
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