Immunocytes do not mediate food intake and the causal relationship with allergic rhinitis: a comprehensive Mendelian randomization
To the best of our knowledge, we are the first to incorporate a large-scale dataset integrating immune cell features, food intake features, and allergic rhinitis into Mendelian randomization analysis. Our research findings indicate that there are causal relationships between six types of food intake and allergic rhinitis, as well as between 30 immune cell phenotypes and allergic rhinitis. Additionally, immune cells do not mediate these relationships.
Authors
- Zhiqiang Zhang (ORCID: https://orcid.org/0000-0002-3993-7330)
- Cheng Wang (ORCID: https://orcid.org/0000-0002-6690-6433)
- Yu-Qi Song
- Jingyang Li (ORCID: https://orcid.org/0000-0001-8271-1575)
- Xinhua Zhu (ORCID: https://orcid.org/0000-0001-8515-4719)
- Dong-Xu Song
- You-Wei Bao
Institutions
- Union Hospital (HK)
- Nanchang University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- Second Affiliated Hospital of Nanchang University (CN)
- First Affiliated Hospital of Nanchang University (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2024-09-27
- DOI
- https://doi.org/10.3389/fnut.2024.1432283
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China