Cognitive impairments in autoimmune encephalitis: the role of autoimmune antibodies and oligoclonal bands
Our results point to OCBs as an additional marker of disease severity in AIE, especially in NMDA receptor-antibody positive patients, possibly indicating a broader inflammatory process, as reflected in elevated CSF lymphocytes. Regular testing for OCBs in cases of suspected AIE may aid in disease prognosis and identification of patients more prone to language and attention disorders, improving diagnosis and targeting treatment for these cognitive aspects.
Authors
- Diana Guber
- Esther Ganelin‐Cohen (ORCID: https://orcid.org/0000-0003-4802-5832)
- Ayal Rozenberg
- Tal Friedman‐Korn
- Yair Wexler (ORCID: https://orcid.org/0000-0002-6270-3188)
- Polina Spector
- Shahar Shelly (ORCID: https://orcid.org/0000-0002-3585-1687)
- Adi Vaknin‐Dembinsky (ORCID: https://orcid.org/0000-0001-8322-1252)
- Lilach Gutter Kapon
- Tal Benoliel-Berman
- Natalya Yarovinsky
Institutions
- Tel Aviv University (IL)
- Technion – Israel Institute of Technology (IL)
- Hebrew University of Jerusalem (IL)
- Sheba Medical Center (IL)
- Rambam Health Care Campus (IL)
- Schneider Children's Medical Center (IL)
- Carmel Medical Center (IL)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-09-27
- DOI
- https://doi.org/10.3389/fimmu.2024.1405337
- Citations
- 11
- Primary Topic
- Autoimmune Neurological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.06