miR-10a regulates cell death and inflammation in adipose tissue of male mice with diet-induced obesity
This study demonstrates the significant role of miR-10a-5p and its downstream target BIM in regulating adipocyte death during diet-induced obesity. This signaling pathway presents a potential therapeutic target for modulating obesity-induced inflammation and cell death in adipose tissue.
Authors
- Cheoljun Choi (ORCID: https://orcid.org/0000-0002-1890-4660)
- S. Kim (ORCID: https://orcid.org/0009-0000-8976-2455)
- Heeseong Kim (ORCID: https://orcid.org/0000-0002-3352-9977)
- Yoon Keun Cho (ORCID: https://orcid.org/0000-0001-8379-3437)
- S. Lee (ORCID: https://orcid.org/0000-0002-3512-4164)
- Yun‐Hee Lee (ORCID: https://orcid.org/0000-0002-0542-4705)
Institutions
- Seoul National University (KR)
- National University College (PR)
Publication Details
- Journal
- Molecular Metabolism
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1016/j.molmet.2024.102039
- Citations
- 9
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 2.57
Funders
- National Research Foundation
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea