Evaluation of changes in the global longitudinal strain for left ventricular function before and after eight weeks of taking high dose of atorvastatin in patients with coronary slow flow phenomenon
The plasma ET-1 levels are elevated in CSFP patients, and atorvastatin improves coronary flow and endothelial function. As evidenced by the results of this study, the daily intake of 40 mg of oral atorvastatin during eight consecutive weeks in patients with CSFP significantly improved LV strain and LV function, however atorvastatin does not have a significant effect on improving the right ventricular function and pulmonary artery systolic pressure.
Authors
- Amir Mohammad Salehi (ORCID: https://orcid.org/0000-0002-1724-6432)
- Zahra Sanaei (ORCID: https://orcid.org/0000-0001-6039-9314)
- Nakisa Khansari (ORCID: https://orcid.org/0000-0002-6272-9492)
- Amirhossein Yazdi (ORCID: https://orcid.org/0000-0003-1235-1433)
- Niloofar Mohammadi (ORCID: https://orcid.org/0009-0009-1626-1567)
Institutions
- Hamedan University of Medical Sciences (IR)
Publication Details
- Journal
- BMC Cardiovascular Disorders
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1186/s12872-024-04198-y
- Citations
- 1
- Primary Topic
- Cardiovascular Function and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.40
Funders
- Hamadan University of Medical Sciences
- Vice Chancellor for Research and Technology, Hamadan University of Medical Sciences