Blunted Cardiac Mitophagy in Response to Metabolic Stress Contributes to HFpEF
Maladaptation to metabolic stress in HFpEF hearts impairs mitochondrial quality control and contributed to the pathogenesis, which can be improved by stimulating fatty acid oxidation.
Authors
- Hongye Chen (ORCID: https://orcid.org/0000-0003-1031-1008)
- Bo Zhou (ORCID: https://orcid.org/0000-0003-1844-7081)
- Rong Tian (ORCID: https://orcid.org/0000-0002-3676-3830)
- P. Wang (ORCID: https://orcid.org/0000-0003-0901-2879)
- Timothy S. McMillen (ORCID: https://orcid.org/0000-0001-5261-3229)
- Charles E. Murry (ORCID: https://orcid.org/0000-0003-3862-6773)
- Yajun Wang (ORCID: https://orcid.org/0009-0003-1774-8744)
- Naoto Muraoka (ORCID: https://orcid.org/0000-0003-0057-0292)
- Melisa Herrero
- Wang Wang (ORCID: https://orcid.org/0000-0001-9093-412X)
- Durba Banerjee (ORCID: https://orcid.org/0000-0003-3905-6178)
- Akira Yoshii
Institutions
- California Institute for Regenerative Medicine (US)
- University of Washington (US)
- World Wide Web Consortium (US)
- Institute for Stem Cell Biology and Regenerative Medicine (IN)
- Regenerative Medicine Institute (MX)
Publication Details
- Journal
- Circulation Research
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1161/circresaha.123.324103
- Citations
- 67
- Primary Topic
- Cardiovascular Function and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 26.94
Funders
- Ohio State University