Serum proinflammatory cytokines, receptor activator of nuclear factor kappa-Β ligand (RANKL), osteoprotegerin (OPG) and RANKL/OPG ratio in mild and severe COVID-19
Serum RANKL/OPG ratio was elevated in COVID-19 individuals and is assumed to be a risk factor for BMD reduction and osteoporosis in these patients. Correlations between IL-1β, TNF-α, ALKp, 25-OH vitamin D, OPG, RANKL, and RANKL/OPG ratio offered the potential role of these proinflammatory markers in the mechanism of osteoporosis in COVID-19 patients.
Authors
- Masome Rabieepour
- Shiva Roshan‐Milani (ORCID: https://orcid.org/0000-0003-1078-9386)
- Roya Naderi (ORCID: https://orcid.org/0000-0001-8529-7306)
- Shahriar Alipour (ORCID: https://orcid.org/0000-0002-2202-9598)
- Siamak Kazemi‐Sufi (ORCID: https://orcid.org/0000-0002-3824-1171)
Institutions
- Urmia University (IR)
- Urmia University of Medical Sciences (IR)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1186/s12879-024-09941-6
- Citations
- 6
- Primary Topic
- Biomarkers in Disease Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.44
Funders
- Urmia University
- Urmia University of Medical Sciences