Comprehensive statistical analysis reveals significant benefits of COVID-19 vaccination in hospitalized patients: propensity score, covariate adjustment, and feature importance by permutation
Vaccinated patients admitted to hospital with COVID-19 had significantly lower mortality and other severe outcomes than unvaccinated ones during the Delta and Omicron waves. These findings have important implications for public health strategies and support the critical importance of vaccination efforts, particularly in low-income countries, where vaccination coverage remains suboptimal.
Authors
- Unaí Tupinambás (ORCID: https://orcid.org/0000-0001-6833-3870)
- Priscilla Pereira dos Reis (ORCID: https://orcid.org/0000-0002-0340-9464)
- Magda Carvalho Pires (ORCID: https://orcid.org/0000-0003-3312-4002)
- Ana Clara Rodrigues da Costa (ORCID: https://orcid.org/0000-0002-7751-6895)
- Aline Gabrielle Sousa Nunes (ORCID: https://orcid.org/0000-0001-8036-0871)
- Rochele Mosmann Menezes (ORCID: https://orcid.org/0000-0002-1548-1607)
- Jessica Moreira (ORCID: https://orcid.org/0000-0002-9693-761X)
- Fernanda Barbosa Lucas (ORCID: https://orcid.org/0000-0003-3926-900X)
- Marcos André Gonçalves (ORCID: https://orcid.org/0000-0002-2075-3363)
- Fernanda d’Athayde Rodrigues (ORCID: https://orcid.org/0000-0001-7368-3592)
- Karen Brasil Ruschel (ORCID: https://orcid.org/0000-0002-0812-920X)
- Fernando Anschau (ORCID: https://orcid.org/0000-0002-2657-5406)
- Guilherme Fonseca (ORCID: https://orcid.org/0009-0000-7862-8701)
- Mônica Aparecida Costa (ORCID: https://orcid.org/0000-0002-2151-5033)
- Pamela Andrea Alves Durães (ORCID: https://orcid.org/0000-0002-5320-8572)
- Giovanna Grünewald Vietta (ORCID: https://orcid.org/0000-0002-0756-3098)
- Euler Roberto Fernandes Manenti (ORCID: https://orcid.org/0000-0003-1592-4727)
- Milena Soriano Marcolino (ORCID: https://orcid.org/0000-0003-4278-3771)
- Leonardo Rocha (ORCID: https://orcid.org/0000-0002-4913-4902)
- Pedro Augusto Van Der Sand Germani (ORCID: https://orcid.org/0000-0001-8274-6938)
- Caroline Lopes de Amorim (ORCID: https://orcid.org/0000-0002-5457-4048)
- Esther Moraes (ORCID: https://orcid.org/0009-0001-4563-3480)
Institutions
- Universidade Federal de Minas Gerais (BR)
- Pontifícia Universidade Católica de Minas Gerais (BR)
- Universidade de Santa Cruz do Sul (BR)
- Centro Universitário de Belo Horizonte (BR)
- Southwest Bahia State University (BR)
- Faculdade Redentor (BR)
- Hospital de Clínicas de Porto Alegre (BR)
- Austrian Institute for Health Technology Assessment GmbH (AT)
- Hospital Nossa Senhora da Conceição (BR)
- Universidade Federal dos Vales do Jequitinhonha e Mucuri (BR)
- Federal University of São João del-Rei (BR)
- Hospital Risoleta Tolentino Neves (BR)
- Instituto Federal Farroupilha (BR)
- Hospital Mãe de Deus (BR)
- Pontifícia Universidade Católica do Rio Grande do Sul (BR)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1186/s12879-024-09865-1
- Citations
- 6
- Primary Topic
- Vaccine Coverage and Hesitancy
- Type
- article
- Field-Weighted Citation Impact
- 3.17
Funders
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Fundação de Amparo à Pesquisa do Estado de Minas Gerais