Incidence and predictors of virological failure among HIV infected children and adolescents receiving second-line antiretroviral therapy in Uganda, a retrospective study
Treatment outcomes for children and adolescents on second-line ART are favourable with one third of them developing virological failure at 10 years of follow up. Adolescent age group and high HIV viral load at the start of second-line ART were significantly associated with virological failure on second-line ART. There is need to determine optimal strategies to improve ART treatment outcomes among adolescents with high viral load counts at second-line ART switch.
Authors
- Ronald Naitala
- Ronald Oceng
- Nelson Kaulukusi Sewankambo (ORCID: https://orcid.org/0000-0001-9362-053X)
- Jacqueline Balungi Kanywa
- Peter Elyanu (ORCID: https://orcid.org/0000-0002-4075-622X)
- Damalie Nakanjako (ORCID: https://orcid.org/0000-0002-0935-2112)
- Esther Nasuuna (ORCID: https://orcid.org/0000-0003-2923-6482)
- Fiona Musiime-Mwase
Institutions
- Baylor College of Medicine Children’s Foundation (UG)
- Infectious Diseases Institute (UG)
- Joint Clinical Research Centre (UG)
- Uganda Protestant Medical Bureau (UG)
- Makerere University (UG)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1186/s12879-024-09930-9
- Citations
- 2
- Primary Topic
- HIV/AIDS Research and Interventions
- Type
- article
- Field-Weighted Citation Impact
- 0.78
Funders
- Afya Bora Consortium