Anti-Mullerian Hormone Induces Foxo1 and Sirt1 Genes Expression in Mouse Ovary
This study demonstrated the capability of AMH to induce <i>Foxo1</i> and <i> Sirt1</i> genes. Moreover, our study revealed the role of AMH in elevating LH serum level which is a main contributor to the pathophysiology of polycystic ovary syndrome, opening new avenues for the study of AMH as a main contributor to the stalled follicular atresia and growth associated with the disease.
Authors
- Ingy M. Hashad (ORCID: https://orcid.org/0000-0001-8265-7353)
- Sahar M. Abdel Maksoud
- Mona Rady (ORCID: https://orcid.org/0000-0002-7561-853X)
- Hoda M. Abouzeid
Institutions
- German University in Cairo (EG)
Publication Details
- Journal
- Current Pharmaceutical Biotechnology
- Published
- 2024-09-27
- DOI
- https://doi.org/10.2174/0113892010293250240917143811
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00