Reproducibility of [18F]MK-6240 kinetics in brain studies with shortened dynamic PET protocol in healthy/cognitively normal subjects
Kinetic modeling of [<sup>18</sup>F]MK-6240 PET can be accurately performed using dynamic scan times as short as 40 min. This can facilitate studies with [<sup>18</sup>F]MK-6240 PET and improve patients accrual. Further work would be necessary to confirm the reproducibility of these results for patients in dementia spectra.
Authors
- Sadek A. Nehmeh (ORCID: https://orcid.org/0000-0002-3129-5003)
- Emily Tanzi (ORCID: https://orcid.org/0000-0002-3633-0680)
- Phelipi Nunes Schuck (ORCID: https://orcid.org/0000-0002-8864-8674)
- Yi Li (ORCID: https://orcid.org/0000-0001-7165-7251)
- Xiuyuan Wang (ORCID: https://orcid.org/0000-0001-6356-3386)
- Sally Xie
Institutions
- Cornell University (US)
Publication Details
- Journal
- EJNMMI Physics
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1186/s40658-024-00679-3
- Primary Topic
- Medical Imaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Institute on Aging