Gender-specific association between circulating serum Klotho and metabolic components in adults

Klotho levels had gender disparities regardless of age, renal function, and sex hormones. In the current cohort, triglycerides were the major component of MetS that was independently associated with serum Klotho levels, and the association was particularly seen in women. However, HDL was found to be the male-specific MetS component independently associated with Klotho.

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Publication Details

Journal
BMC Endocrine Disorders
Published
2024-09-27
DOI
https://doi.org/10.1186/s12902-024-01737-8
Citations
7
Primary Topic
Parathyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
2.37

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article

Gender-specific association between circulating serum Klotho and metabolic components in adults

Zheng Wang, Zhenzhen Wang, Hang Zhang, Lei Shi et al.
7 citations
BMC Endocrine Disorders
Parathyroid Disorders and Treatments
2.37
article

Gender-specific association between circulating serum Klotho and metabolic components in adults

Zheng Wang, Zhenzhen Wang, Hang Zhang, Lei Shi, Gui-xia Zheng
article en
7 citations

Abstract

Klotho levels had gender disparities regardless of age, renal function, and sex hormones. In the current cohort, triglycerides were the major component of MetS that was independently associated with serum Klotho levels, and the association was particularly seen in women. However, HDL was found to be the male-specific MetS component independently associated with Klotho.

BMC Endocrine DisordersVol. 24(1)
Heilongjiang Provincial Hospital (CN), Xijing Hospital (CN), Hangzhou Medical College (CN), Air Force Medical University (CN)
National Natural Science Foundation of China, Zhejiang Provincial Program for the Cultivation of High-Level Innovative Health Talents
Gender equality
Openalex Percentile: Top 9%
Parathyroid Disorders and Treatments
2.37
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Gender-specific association between circulating serum Klotho and metabolic components in adults — Zheng Wang, Zhenzhen Wang, et al. · BMC Endocrine Disorders (2024) | TGRS Research Map | TGRS