Association between hydroxychloroquine intake and damage to the outer nuclear layer in eyes without manifest retinal toxicity
The thickness of the ONL can significantly decrease in patients taking HCQ, even in the absence of of manifest retinal toxicity. This study is the first to evaluate this association in eyes with negative screening and diagnostic tests for HCQ retinopathy. The findings suggest that ONL thickness could serve as an early diagnostic indicator for HCQ retinal toxicity.
Authors
- Joseph Nehme (ORCID: https://orcid.org/0000-0002-4740-7663)
- Carla Abi Doumit (ORCID: https://orcid.org/0009-0000-4362-6378)
- Edmond Jalkh (ORCID: https://orcid.org/0000-0002-4305-0492)
- Nagib Salameh
Institutions
- Holy Spirit University of Kaslik (LB)
- He Eye Hospital (CN)
Publication Details
- Journal
- BMC Ophthalmology
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1186/s12886-024-03684-3
- Citations
- 3
- Primary Topic
- Drug-Induced Ocular Toxicity
- Type
- article
- Field-Weighted Citation Impact
- 1.62