Three new cyclopentanoid monoterpenes from the roots of <i>Picrorhiza scrophulariiflora</i>
Three new cyclopentanoid monoterpenes, neopiscrocins A-C (<b>1</b>-<b>3</b>), together with 14 known compounds (<b>4</b>-<b>17</b>), were isolated from the roots of <i>Picrorhiza scrophulariiflora</i>. The structres of these compounds were elucidated on the basis of their spectroscopic data. All compounds were evaluated for cytotoxicity against six human tumor cell lines (PC9, PANC1, HCT-116, Hep-G2, BGC-823, and MCF-7), hepatoprotective activity and anti-inflammatory activity.
Authors
- Guo-Ru Shi
- Wanqi Zhang (ORCID: https://orcid.org/0000-0002-6044-1137)
- Xinyue Li (ORCID: https://orcid.org/0000-0002-7319-6302)
- Ming-Hui Sun
- Yanfei Liu (ORCID: https://orcid.org/0000-0003-3708-0238)
- De‐Quan Yu (ORCID: https://orcid.org/0000-0003-4774-6419)
- Jinghan Zhang (ORCID: https://orcid.org/0000-0003-0058-6518)
- Xinli Ma (ORCID: https://orcid.org/0000-0003-3784-0241)
- Jie Zhou
- Gu Zhao
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
Publication Details
- Journal
- Journal of Asian Natural Products Research
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1080/10286020.2024.2408547
- Citations
- 2
- Primary Topic
- Phytochemistry and Biological Activities
- Type
- article
- Field-Weighted Citation Impact
- 1.20
Funders
- Chinese Academy of Medical Sciences Initiative for Innovative Medicine