Rod-shaped mesoporous silica nanoparticles reduce bufalin cardiotoxicity and inhibit colon cancer by blocking lipophagy
rMSNs reduced BA-mediated cardiotoxicity and impaired the growth of colon cancer cells. Mechanistically, antitumor activity depends on lipophagy.
Authors
- Yibao Fan
- Zoya Iqbal (ORCID: https://orcid.org/0009-0004-5710-174X)
- Xianbin Zhang (ORCID: https://orcid.org/0000-0002-0948-6698)
- Xinxin Li (ORCID: https://orcid.org/0000-0002-3026-8185)
- Peng Liu (ORCID: https://orcid.org/0000-0002-2529-8726)
- Hongxia Dong (ORCID: https://orcid.org/0009-0006-8413-1842)
- Wei Zhang (ORCID: https://orcid.org/0000-0003-4423-1030)
- Zhuolin Wu (ORCID: https://orcid.org/0000-0002-8938-894X)
- Peng Gong (ORCID: https://orcid.org/0000-0003-1943-1014)
- Qianyou Li
- Zhiyin Lin (ORCID: https://orcid.org/0009-0003-5079-9850)
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Shenzhen University (CN)
- Chinese PLA General Hospital (CN)
- Shantou University (CN)
- International Network for Cancer Treatment and Research (BE)
- First Affiliated Hospital of Shantou University Medical College (CN)
- Chinese University of Hong Kong, Shenzhen (CN)
Publication Details
- Journal
- Lipids in Health and Disease
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1186/s12944-024-02301-y
- Citations
- 6
- Primary Topic
- Curcumin's Biomedical Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.02
Funders
- Shenzhen University
- Sanming Project of Medicine in Shenzhen