Increased nocturnal urinary cortisol levels in the elderly patients with depression, coexisting major geriatric syndromes and combined pathogenetic mechanisms
The depression in elderly patient should be reconsidered as a systemic disease, with coexisting major geriatric syndromes (disability, dementia, frailty) and combined pathogenetic mechanisms (metabolic syndrome, impaired renal function, low-grade inflammation, and allostatic load). Cortisol confirmed its role as principal mediator of the aging process in both dementia and metabolic syndrome.
Authors
- Antonio Martocchia (ORCID: https://orcid.org/0000-0002-6201-5377)
- Lavinia Toussan
- Ligia J. Domínguez (ORCID: https://orcid.org/0000-0003-1466-8610)
- Giovambattista Desideri (ORCID: https://orcid.org/0000-0002-0145-1271)
- Maurizio Gallucci (ORCID: https://orcid.org/0000-0001-6329-3195)
- Manuela Stefanelli (ORCID: https://orcid.org/0000-0001-8563-8043)
- Claudio Ferri (ORCID: https://orcid.org/0000-0002-3594-2503)
- Demetrio Postacchini (ORCID: https://orcid.org/0000-0001-5239-2702)
- P. Falaschi
- Mario Barbagallo (ORCID: https://orcid.org/0000-0002-1349-6530)
- Stefania Maggi (ORCID: https://orcid.org/0000-0002-0453-8663)
- Giuseppe Paolisso (ORCID: https://orcid.org/0000-0002-2137-455X)
- A. Proietti (ORCID: https://orcid.org/0000-0002-8863-8863)
- Marianna Noale
- Giulia M Falaschi
- Maurizio Cassol
- Francesca Pastore
Institutions
- University of Campania "Luigi Vanvitelli" (IT)
- University of L'Aquila (IT)
- Parco Nazionale d'Abruzzo (IT)
- AULSS 2 Marca Trevigiana (IT)
- Azienda Ospedaliera G.Rummo (IT)
- Fatebenefratelli Hospital (IT)
- Neuroscience Institute (IT)
- Azienda Ospedaliera Sant'Andrea (IT)
- Casa di Cura Città di Roma (IT)
- National Research Council (IT)
- Istituto Nazionale di Riposo e Cura per Anziani (IT)
- Sapienza University of Rome (IT)
- University of Palermo (IT)
Publication Details
- Journal
- Aging Clinical and Experimental Research
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1007/s40520-024-02849-w
- Citations
- 4
- Primary Topic
- Stress Responses and Cortisol
- Type
- article
- Field-Weighted Citation Impact
- 1.17