Integrating randomized controlled trials and non-randomized studies of interventions to assess the effect of rare events: a Bayesian re-analysis of two meta-analyses
Our study showed that including NRSIs in a meta-analysis of RCTs for rare events could increase the certainty and comprehensiveness of the evidence. The estimates obtained from NRSIs are generally considered to be biased, and the possible influence of NRSIs on the certainty of the combined evidence needs to be carefully investigated.
Authors
- Yu Ma (ORCID: https://orcid.org/0000-0003-2175-3346)
- Fan Mei (ORCID: https://orcid.org/0000-0002-3707-8800)
- Minghong Yao (ORCID: https://orcid.org/0000-0001-8151-6014)
- Yun Zhou (ORCID: https://orcid.org/0000-0003-1690-5560)
- Xin Sun (ORCID: https://orcid.org/0000-0002-6554-7088)
- Kang Zou (ORCID: https://orcid.org/0000-0002-4959-1951)
- Ling Li (ORCID: https://orcid.org/0000-0002-1940-8693)
- Jiayidaer Huan
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- BMC Medical Research Methodology
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1186/s12874-024-02347-7
- Citations
- 4
- Primary Topic
- Meta-analysis and systematic reviews
- Type
- article
- Field-Weighted Citation Impact
- 1.85
Funders
- National Natural Science Foundation of China
- National Science Fund for Distinguished Young Scholars