Precision molecular insights for prostate cancer prognosis: tumor immune microenvironment and cell death analysis of senescence-related genes by machine learning and single-cell analysis
This study presents a robust ARGs-based risk score model for predicting biochemical recurrence in PCa patients, highlighting the potential significance of aging genes in PCa prognosis and offering enhanced predictive accuracy compared to traditional clinical parameters. These findings open new avenues for research on PCa recurrence prediction and therapeutic strategies.
Authors
- Yuni Wu (ORCID: https://orcid.org/0000-0003-1145-3729)
- Zhi‐Bin Luo (ORCID: https://orcid.org/0000-0002-0389-9221)
- Ran Xu (ORCID: https://orcid.org/0009-0000-8023-0495)
- Jing Wang (ORCID: https://orcid.org/0000-0001-7431-8925)
Institutions
- North Sichuan Medical University (CN)
- Chongqing University (CN)
- First People's Hospital of Chongqing (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1007/s12672-024-01277-6
- Citations
- 1
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.42