Precision molecular insights for prostate cancer prognosis: tumor immune microenvironment and cell death analysis of senescence-related genes by machine learning and single-cell analysis

This study presents a robust ARGs-based risk score model for predicting biochemical recurrence in PCa patients, highlighting the potential significance of aging genes in PCa prognosis and offering enhanced predictive accuracy compared to traditional clinical parameters. These findings open new avenues for research on PCa recurrence prediction and therapeutic strategies.

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Publication Details

Journal
Discover Oncology
Published
2024-09-27
DOI
https://doi.org/10.1007/s12672-024-01277-6
Citations
1
Primary Topic
Prostate Cancer Treatment and Research
Type
article
Field-Weighted Citation Impact
0.42
Controls
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article

Precision molecular insights for prostate cancer prognosis: tumor immune microenvironment and cell death analysis of senescence-related genes by machine learning and single-cell analysis

Yuni Wu, Zhi‐Bin Luo, Ran Xu, Jing Wang
1 citations
Discover Oncology
Prostate Cancer Treatment and Research
0.42
article

Precision molecular insights for prostate cancer prognosis: tumor immune microenvironment and cell death analysis of senescence-related genes by machine learning and single-cell analysis

Yuni Wu, Zhi‐Bin Luo, Ran Xu, Jing Wang
article en
1 citations

Abstract

This study presents a robust ARGs-based risk score model for predicting biochemical recurrence in PCa patients, highlighting the potential significance of aging genes in PCa prognosis and offering enhanced predictive accuracy compared to traditional clinical parameters. These findings open new avenues for research on PCa recurrence prediction and therapeutic strategies.

Discover OncologyVol. 15(1)
North Sichuan Medical University (CN), Chongqing University (CN), First People's Hospital of Chongqing (CN)
Good health and well-being
Openalex Percentile: Top 32%
Prostate Cancer Treatment and Research
0.42
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