Early Recognition and Management of Ocular Manifestations of Toxic Epidermal Necrolysis in a Pediatric Patient: A Case Report

Toxic epidermal necrolysis (TEN) is a severe, often drug-induced mucocutaneous reaction characterized by widespread epidermal necrosis and detachment. Ocular involvement is common and can lead to significant morbidity if not addressed promptly. This case report presents a 10-year-old female with fever, rash, and severe ocular symptoms. Early use of Prokera, an amniotic membrane device, was instrumental in managing her ocular condition. After discharge and follow-up care, the patient showed marked improvement. This case highlights the importance of early recognition and intervention in ocular manifestations of TEN to prevent long-term complications.

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Journal
Cureus
Published
2024-09-27
DOI
https://doi.org/10.7759/cureus.70323
Citations
2
Primary Topic
Drug-Induced Adverse Reactions
Type
article
Field-Weighted Citation Impact
0.90
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article

Early Recognition and Management of Ocular Manifestations of Toxic Epidermal Necrolysis in a Pediatric Patient: A Case Report

Yazeed J AlHaqbani, Fatema K Abulfateh, Abdulrahman S Albuainain
2 citations
Cureus
Drug-Induced Adverse Reactions
0.90
article

Early Recognition and Management of Ocular Manifestations of Toxic Epidermal Necrolysis in a Pediatric Patient: A Case Report

Yazeed J AlHaqbani, Fatema K Abulfateh, Abdulrahman S Albuainain
article en
2 citations

Abstract

Toxic epidermal necrolysis (TEN) is a severe, often drug-induced mucocutaneous reaction characterized by widespread epidermal necrosis and detachment. Ocular involvement is common and can lead to significant morbidity if not addressed promptly. This case report presents a 10-year-old female with fever, rash, and severe ocular symptoms. Early use of Prokera, an amniotic membrane device, was instrumental in managing her ocular condition. After discharge and follow-up care, the patient showed marked improvement. This case highlights the importance of early recognition and intervention in ocular manifestations of TEN to prevent long-term complications.

CureusVol. 16(9)
Defence Terrain Research Laboratory (IN)
Good health and well-being
Openalex Percentile: Top 23%
Drug-Induced Adverse Reactions
0.90
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Early Recognition and Management of Ocular Manifestations of Toxic Epidermal Necrolysis in a Pediatric Patient: A Case Report — Yazeed J AlHaqbani, Fatema K Abulfateh, et al. · Cureus (2024) | TGRS Research Map | TGRS