Cerebrospinal fluid markers of neuroinflammation and coagulation in severe cerebral edema and chronic hydrocephalus after subarachnoid hemorrhage: a prospective study
Elevated levels of inflammatory cytokines and extrinsic coagulation pathway factors in the CSF are associated with the development of early severe cerebral edema and chronic hydrocephalus following SAH. These factors are interrelated and may contribute to post-SAH glymphatic-meningeal lymphatic dysfunction.
Authors
- Anke Zhang (ORCID: https://orcid.org/0000-0002-0007-7724)
- Luxi Chen (ORCID: https://orcid.org/0000-0001-7802-9215)
- Yuanjian Fang (ORCID: https://orcid.org/0000-0002-0035-6045)
- Sheng Chen (ORCID: https://orcid.org/0000-0002-8374-136X)
- John H. Zhang (ORCID: https://orcid.org/0000-0002-4319-4285)
- Junjie Wang (ORCID: https://orcid.org/0000-0002-1388-076X)
- Jianmin Zhang (ORCID: https://orcid.org/0000-0002-3184-1502)
- Yibo Liu (ORCID: https://orcid.org/0000-0003-2680-9185)
- Haocheng Zhang (ORCID: https://orcid.org/0000-0002-2209-3629)
- Xiaoyu Wang (ORCID: https://orcid.org/0000-0002-9075-1769)
- Jun Yu
- Sixuan Tian
- Jiahao Zhang (ORCID: https://orcid.org/0009-0001-4571-5427)
Institutions
- Loma Linda University (US)
- Zhejiang Lab (CN)
- Zhejiang Center for Disease Control and Prevention (CN)
- Molecular Devices (United Kingdom) (GB)
- Second Affiliated Hospital of Zhejiang University (CN)
- South China University of Technology (CN)
Publication Details
- Journal
- Journal of Neuroinflammation
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1186/s12974-024-03236-y
- Citations
- 31
- Primary Topic
- Intracranial Aneurysms: Treatment and Complications
- Type
- article
- Field-Weighted Citation Impact
- 11.44
Funders
- National Natural Science Foundation of China