Reduced Platelet Activation in Triple-Negative Essential Thrombocythemia Compared with <i>JAK2V617F</i> -Mutated Essential Thrombocythemia
In comparison with JAK2V617F-mutated ET, TN-ET is associated with lower platelet ROS levels, which leads to reduced platelet activation and consequently a lower risk of thrombosis.
Authors
- Xiaofan Liu (ORCID: https://orcid.org/0000-0002-9911-4491)
- Ying Chi (ORCID: https://orcid.org/0009-0007-9262-0408)
- Ting Sun (ORCID: https://orcid.org/0000-0003-3997-6062)
- Hu Zhou (ORCID: https://orcid.org/0000-0001-5259-1429)
- H. Dong (ORCID: https://orcid.org/0000-0002-1783-711X)
- Renchi Yang (ORCID: https://orcid.org/0000-0003-3741-8518)
- Xinyue Dai (ORCID: https://orcid.org/0000-0003-0570-1810)
- Yueting Huang (ORCID: https://orcid.org/0000-0002-7714-0672)
- Wenjing Gu (ORCID: https://orcid.org/0000-0003-1604-7666)
- Feng Xue (ORCID: https://orcid.org/0000-0002-5947-3924)
- Donglei Zhang (ORCID: https://orcid.org/0000-0003-1581-0439)
- Mankai Ju (ORCID: https://orcid.org/0000-0002-3570-8389)
- Wentian Wang (ORCID: https://orcid.org/0000-0002-2721-2447)
- Rongfeng Fu (ORCID: https://orcid.org/0000-0001-5442-1028)
- Jia Chen (ORCID: https://orcid.org/0000-0002-7096-1056)
- Wei Liu (ORCID: https://orcid.org/0000-0003-4713-2441)
- Huiyuan Li (ORCID: https://orcid.org/0000-0003-3242-1742)
- Xian Zhang (ORCID: https://orcid.org/0000-0002-2691-5247)
- Lei Zhang (ORCID: https://orcid.org/0000-0001-7769-7377)
- Yunfei Chen (ORCID: https://orcid.org/0000-0001-7309-8545)
- Jing Zhang (ORCID: https://orcid.org/0009-0004-7391-4118)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Wuhan University (CN)
- Zhengzhou University (CN)
- First Affiliated Hospital of Xiamen University (CN)
- Zhongnan Hospital of Wuhan University (CN)
- Henan Cancer Hospital (CN)
- Institute of Hematology & Blood Diseases Hospital (CN)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1158/1078-0432.ccr-24-1731
- Citations
- 1
- Primary Topic
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.44