Heterologous expression of the Oenococcus oeni two-component signal transduction response regulator in the Lactiplantibacillus plantarum WCFS1 strain enhances acid stress tolerance
These results indicated that the recombinant strain enhances acid stress tolerance by regulating a gene expression pattern, increasing ATP consumption, and enhancing cell membrane fluidity, membrane permeability, and membrane integrity at specific growth stages. Thus, the recombinant strain may have potential application in the microbial biotechnology industry.
Authors
- Yifan Zhao (ORCID: https://orcid.org/0000-0003-1011-395X)
- Hongyu Zhao (ORCID: https://orcid.org/0000-0003-1477-5731)
- Weiyu Song (ORCID: https://orcid.org/0009-0007-6257-3831)
- Longxiang Liu (ORCID: https://orcid.org/0000-0002-1517-165X)
- Yumiao Zhang (ORCID: https://orcid.org/0000-0002-9619-6153)
- Yujuan Zheng (ORCID: https://orcid.org/0000-0003-0510-9104)
- Xiaoqiu Wu
- Junhua Liu
- Bin Liu
- Huan Wang (ORCID: https://orcid.org/0000-0003-2596-9013)
Institutions
- Shangdong Agriculture and Engineering University (CN)
- Binzhou People's Hospital (CN)
- ES Technology (United Kingdom) (GB)
- Institute of New Materials (CN)
- Northwest A&F University (CN)
Publication Details
- Journal
- BMC Microbiology
- Published
- 2024-09-28
- DOI
- https://doi.org/10.1186/s12866-024-03498-9
- Citations
- 4
- Primary Topic
- Probiotics and Fermented Foods
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- National Natural Science Foundation of China
- Binzhou University
- Science and Technology Support Plan for Youth Innovation of Colleges and Universities of Shandong Province of China