CircLIFRSA/miR-1305/PTEN axis attenuates malignant cellular processes in non-small cell lung cancer by regulating AKT phosphorylation
These findings indicate that circLIFRSA/miR-1305/PTEN axis attenuates malignant processes by regulating AKT phosphorylation, and provide new insights into the potential of circLIFRSA as a biomarker for early diagnosis and as a promising therapeutic target in NSCLC.
Authors
- Meina Jiang
- Zhaohui Gong
- Shuai Fang (ORCID: https://orcid.org/0000-0002-9364-6462)
- Huihui Bai
- Weiyu Shen (ORCID: https://orcid.org/0000-0003-3756-5083)
- Chengwei Zhou (ORCID: https://orcid.org/0000-0002-7764-7377)
Institutions
- Ningbo University (CN)
- Ningbo Medical Center Lihuili Hospital (CN)
- Ningbo University Affiliated Hospital (CN)
- Ningbo First Hospital (CN)
Publication Details
- Journal
- Molecular Cancer
- Published
- 2024-09-28
- DOI
- https://doi.org/10.1186/s12943-024-02120-w
- Citations
- 11
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 2.57
Funders
- Ningbo University