Estimating pneumococcal carriage dynamics in adults living with HIV in a mature infant pneumococcal conjugate vaccine programme in Malawi, a modelling study
The disproportionately high point prevalence of pneumococcal carriage in ALWHIV on ART > 1y is likely due to impaired nasopharyngeal clearance, which results in prolonged carriage. Our findings provide baseline estimates for comparing pneumococcal carriage dynamics after implementing new PCV strategies in ALWHIV.
Authors
- Mercy Khwiya
- Ndaona Mitole
- Chrispin Chaguza (ORCID: https://orcid.org/0000-0002-2108-1757)
- Ken Malisita
- Daniela M. Ferreira (ORCID: https://orcid.org/0000-0002-0594-0902)
- Joseph Phiri (ORCID: https://orcid.org/0000-0002-8999-4501)
- Kondwani Jambo (ORCID: https://orcid.org/0000-0002-3195-2210)
- Lusako Sibale (ORCID: https://orcid.org/0000-0001-5378-3561)
- Deus Thindwa (ORCID: https://orcid.org/0000-0003-4845-7862)
- Lukerensia Mlongoti
- Alice Kusakala
- Edwin Lisimba
- Prosperina Kapwata
- Thokozani Kayembe
Institutions
- University of Liverpool (GB)
- Liverpool School of Tropical Medicine (GB)
- Malawi-Liverpool-Wellcome Trust Clinical Research Programme (MW)
- Kamuzu Central Hospital (MW)
- Yale University (US)
- University of Oxford (GB)
- Queen Elizabeth Central Hospital (MW)
Publication Details
- Journal
- BMC Medicine
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1186/s12916-024-03631-5
- Citations
- 7
- Primary Topic
- Pneumonia and Respiratory Infections
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- Medical Research Council