Induction of human stem cells into ameloblasts by reaggregation strategy
This study establishes a simplified yet highly effective cell-cell reaggregation strategy for inducing stem cells to support tooth formation and differentiate into functional ameloblasts, paving the way for novel approaches for the development of stem cell-based tooth organoids and bioengineered tooth germs in vitro.
Authors
- Chensheng Lin (ORCID: https://orcid.org/0000-0001-7898-6648)
- Minjun Huang (ORCID: https://orcid.org/0000-0003-1307-9283)
- Yanding Zhang (ORCID: https://orcid.org/0000-0002-9090-3670)
- Shiyu Liu (ORCID: https://orcid.org/0000-0003-0208-8635)
- Xuefeng Hu
Institutions
- Fujian Normal University (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1186/s13287-024-03948-1
- Citations
- 2
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.88
Funders
- National Natural Science Foundation of China
- Fujian Medical University