Characterization and angiogenic potential of CD146+ endometrial stem cells
The study highlights the angiogenic potential of endometrial stem cells, particularly the CD146<sup>+</sup> cell population. These cells promote angiogenesis, secreting growth factors and forming stable blood vessel structures. CD146<sup>+</sup> cells have higher expression levels of VEGF and TGF-α, key factors in angiogenesis. This suggests CD146<sup>+</sup> eSCs may be promising for therapeutic applications in vascular diseases requiring angiogenesis. Further research is needed.
Authors
- Indumathi Somasundaram (ORCID: https://orcid.org/0000-0001-6288-4559)
- Meghnad G. Joshi (ORCID: https://orcid.org/0000-0001-6060-244X)
- Tejas B. Marsale (ORCID: https://orcid.org/0000-0002-7160-1431)
- Priyanka Hilage
- Apurva Birajdar
- Rakesh K. Sharma (ORCID: https://orcid.org/0000-0002-0984-8281)
- Dhanashree Patil (ORCID: https://orcid.org/0000-0003-2498-2611)
- Gaurang Telang (ORCID: https://orcid.org/0000-0002-2220-5360)
- Ashwini Mane Patil
Institutions
- ASTER (CA)
- nLIGHT (United States) (US)
- Dr. D. Y. Patil Medical College, Hospital and Research Centre (IN)
- KLE Academy of Higher Education and Research (IN)
- Department of Commerce (AU)
- KLE Society Hospital (IN)
- D.Y. Patil Education Society (IN)
- Io Therapeutics (United States) (US)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1186/s13287-024-03918-7
- Citations
- 10
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 4.38
Funders
- D.Y. Patil Education Society Institution Deemed to be University Kolhapur