Synergistic combinations of novel polymyxins and rifampicin with improved eradication of colistin-resistant Pseudomonas aeruginosa biofilms
The present study showed <i>in vitro</i> efficacy of CEP938 against both colistin-susceptible and colistin-resistant <i>P. aeruginosa</i> biofilms as well as an ability of CEP938 to synergize with rifampicin in biofilm eradication.
Authors
- Oana Ciofu (ORCID: https://orcid.org/0000-0001-5648-4858)
- Claus Ernst Moser (ORCID: https://orcid.org/0000-0002-7664-8570)
- Henrik Franzyk (ORCID: https://orcid.org/0000-0002-2822-1927)
- Niels Høiby (ORCID: https://orcid.org/0000-0002-1347-725X)
- Johan Storm Jørgensen
- Anne Sofie Laulund Siebert
Institutions
- University of Copenhagen (DK)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
Publication Details
- Journal
- Biofilm
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1016/j.bioflm.2024.100224
- Citations
- 5
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.85
Funders
- Novo Nordisk
- Novo Nordisk Fonden