Physiologically-based pharmacokinetic modelling in sepsis: A tool to elucidate how pathophysiology affects meropenem pharmacokinetics
These findings may be extended to more diverse drug types and support a more mechanistic understanding of the effect of sepsis on drug exposure.
Authors
- Matthias Gijsen (ORCID: https://orcid.org/0000-0003-1378-3772)
- Salma M. Bahnasawy
- Elisabet I. Nielsen (ORCID: https://orcid.org/0000-0003-0725-214X)
- Neil John Parrott (ORCID: https://orcid.org/0000-0001-6821-7714)
- Lena E. Friberg (ORCID: https://orcid.org/0000-0002-2979-679X)
- Isabel Spriet (ORCID: https://orcid.org/0000-0001-6342-0676)
Institutions
- Roche (Switzerland) (CH)
- Uppsala University (SE)
- KU Leuven (BE)
Publication Details
- Journal
- International Journal of Antimicrobial Agents
- Published
- 2024-09-28
- DOI
- https://doi.org/10.1016/j.ijantimicag.2024.107352
- Citations
- 5
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 2.24
Funders
- European Commission
- H2020 Marie Skłodowska-Curie Actions