Intravenous methylprednisolone for nephrotic syndrome with minimal change lesions: a randomized controlled trial
This study suggested that highly oedematous MCNS patients who received IV isovalent methylprednisolone induction therapy followed by oral prednisone achieved earlier remission than the conventional oral prednisone regimen without differences in relapse rates or adverse effects. Short-term IV methylprednisolone followed by oral prednisone may be a better choice for MCNS patients with severe oedema.
Authors
- Hua Guo (ORCID: https://orcid.org/0000-0002-3345-8005)
- Cuiwei Yao
- Jialu Liu (ORCID: https://orcid.org/0000-0002-2956-7436)
- Tianyu Zhu (ORCID: https://orcid.org/0000-0002-4781-7398)
- Jinxia Chen (ORCID: https://orcid.org/0000-0001-8264-9759)
- Yongzhi Xu
- Ruting Li
Institutions
- Guangdong Medical College (CN)
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
- Dongguan People’s Hospital (CN)
- Boai Hospital of Zhongshan (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Nephrology Dialysis Transplantation
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1093/ndt/gfae208
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 0.00