Does pre-irradiation gross tumor volume predict the risk of progression after radiation therapy in pediatric patients with adamantinomatous craniopharyngioma?
The authors conclude that for most children and adolescents with ACP, the GTV at the initiation of RT is not associated with the risk of PD. This finding may influence surgical practice, because it suggests that aggressive tumor debulking for the purpose of improving the efficacy of RT may not be necessary. In the case of giant tumors, however, novel strategies may be needed for tumor control.
Authors
- Susan Staulcup
- Kathleen Dorris (ORCID: https://orcid.org/0000-0003-0753-2176)
- Dexiang Gao (ORCID: https://orcid.org/0000-0003-3920-7060)
- Eric Prince (ORCID: https://orcid.org/0000-0001-7359-6608)
- Kareem Fakhoury (ORCID: https://orcid.org/0000-0003-3885-3968)
- Todd C. Hankinson (ORCID: https://orcid.org/0000-0002-6288-9496)
- David M. Mirsky (ORCID: https://orcid.org/0000-0003-2162-515X)
- Narine Wandrey (ORCID: https://orcid.org/0000-0002-1915-3010)
- Sarah A. Milgrom
- Tamar Brooks
- Elizabeth Ignowski
- Марина Москаленко
- Karlie Boone
Institutions
- Touro College (US)
- Morgan Adams Foundation (US)
- Children's Hospital Colorado (US)
- Center for Cancer and Blood Disorders (US)
- University of Colorado Cancer Center (US)
- Neurological Surgery (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- Journal of Neurosurgery Pediatrics
- Published
- 2024-09-28
- DOI
- https://doi.org/10.3171/2024.7.peds2429
- Primary Topic
- Pituitary Gland Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00